Allium genus plants, such as leek (Allium porrum), are rich sources of anti-inflammatory\nand anti-oxidant secondary metabolites; this is of interest because it demonstrates their\nsuitability as pharmacological alternatives for inflammatory processes, including allergy treatment.\nThe composition of methanolic leek extract (LE) was analyzed by GC-MS and LC-IT/MS, and\nthe total phenolic content and antioxidant capacity were quantified by colorimetric methods.\nIts pharmacological potential was analyzed in human bronchial epithelial Calu-3 cells, human\nmast cells LAD2, and humanized rat basophiles RBL-2H3. LE exhibited a cytotoxic effect on\nCalu-3 cells and HumRBL-2H3 cells only at high concentrations and in a dose-dependent manner.\nMoreover, LE decreased the degranulation of LAD2 and HumRBL-2H3 cells.... .............
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